Transcription Factor Regulatory Networks (Methods in Molecular Biology Book 2594)
Transcription Factor Regulatory Networks (Methods in Molecular Biology Book 2594) is an advanced, practical guide designed for molecular biologists, geneticists, bioinformaticians, and biomedical researchers exploring the complex regulatory systems that control gene expression. This volume provides state-of-the-art protocols, experimental workflows, and computational tools for mapping and analyzing transcription factor (TF) networks across various biological systems.
Part of the highly respected Methods in Molecular Biology series, this book delivers step-by-step protocols that are fully tested and reproducible, making it a trusted resource for both newcomers and experienced researchers. It covers the latest techniques for identifying transcription factors, mapping binding sites, characterizing DNA–protein interactions, and integrating these data into functional regulatory networks.
Key Features:
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Comprehensive TF network analysis – From experimental detection to computational modeling.
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Step-by-step laboratory protocols – Detailed methods for ChIP-seq, DNA footprinting, and electrophoretic mobility shift assays (EMSAs).
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Integration of bioinformatics tools – Methods for network reconstruction, visualization, and statistical analysis.
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Applications in biomedical research – Including cancer genomics, developmental biology, and disease biomarker discovery.
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Expert authorship – Written by leading scientists in gene regulation and systems biology.
