Model Systems in Biology: History, Philosophy, and Practical Concerns
Model Systems in Biology: History, Philosophy, and Practical Concerns is an insightful and comprehensive exploration of the organisms and experimental systems that have shaped our understanding of biology. This authoritative book examines the historical development, philosophical foundations, and practical applications of model systems—ranging from bacteria and yeast to fruit flies, zebrafish, and mice—used in laboratory research worldwide.
By blending history of science, philosophy, and experimental methodology, the author provides a unique perspective on why certain species become “models” in biological research and how they continue to guide scientific discovery. Readers will gain an understanding of how model systems influence hypothesis generation, experimental design, and the interpretation of results, as well as the ethical and logistical considerations involved in their use.
Key Features of “Model Systems in Biology”:
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Historical Context: Traces the development of iconic model organisms from early biology to modern research.
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Philosophical Insights: Discusses conceptual issues such as representativeness, extrapolation, and the limitations of model systems.
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Diverse Examples: Covers microbial, plant, and animal model systems used in genetics, developmental biology, neuroscience, and evolutionary studies.
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Practical Concerns: Examines experimental design, reproducibility, and the challenges of maintaining model organisms.
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Ethical Considerations: Addresses welfare, sustainability, and alternative approaches to traditional models.
