RNA Structure and Dynamics (Methods in Molecular Biology Book 2568)

RNA Structure and Dynamics (Volume 2568 in the Methods in Molecular Biology series) is a comprehensive, hands-on guide for studying RNA at structural, biochemical, and dynamic levels. This essential laboratory manual brings together cutting-edge methodologies that empower researchers to investigate RNA folding, conformational transitions, molecular interactions, and functional regulation.

Edited by leading experts in RNA biology, the book offers step-by-step experimental protocols designed for accuracy, reproducibility, and adaptability to diverse research goals. Whether you work in structural biology, molecular genetics, or biophysics, this volume serves as an indispensable reference for RNA-focused research.

Key Features:

  • Step-by-Step Protocols – Reproducible experimental procedures for RNA analysis.

  • Advanced Techniques – Includes NMR spectroscopy, cryo-EM, X-ray crystallography, chemical probing, SHAPE mapping, and single-molecule methods.

  • Dynamic Perspective – Focus on conformational flexibility and folding pathways of RNA.

  • Troubleshooting & Tips – Practical advice from experienced researchers to avoid common pitfalls.

  • Comprehensive Coverage – From in vitro assays to cellular and in vivo RNA structural studies.