The Centrosome and its Functions and Dysfunctions (Advances in Anatomy, Embryology and Cell Biology Book 235)
The Centrosome and Its Functions and Dysfunctions (Book 235 in the renowned Advances in Anatomy, Embryology and Cell Biology series) offers a comprehensive exploration of one of the cell’s most vital organelles — the centrosome. This book presents an in-depth examination of the centrosome’s structure, roles in cell division, and regulatory mechanisms, as well as the impact of its dysfunctions on various diseases, including cancer, neurodevelopmental disorders, and ciliopathies.
Authored by leading researchers in cell biology, molecular medicine, and developmental biology, this authoritative text integrates the latest scientific discoveries with foundational knowledge to provide readers with a complete understanding of centrosomal biology. It is an essential resource for cell biologists, geneticists, oncologists, and biomedical researchers interested in cellular organization, mitosis, and human disease.
Key Features:
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Detailed Overview of Centrosome Biology: Explains the centrosome’s architecture, duplication cycle, and its central role in microtubule organization and spindle formation.
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Focus on Cellular Mechanisms: Covers key processes such as centrosome maturation, centriole biogenesis, and cilia formation.
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Insights into Disease Mechanisms: Examines how centrosomal dysfunction contributes to tumorigenesis, brain malformations, and inherited syndromes.
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Recent Research Highlights: Includes the latest findings in centrosome regulation, signaling pathways, and links to genome stability.
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Illustrative Figures & Models: Contains high-quality microscopy images, structural diagrams, and schematic representations to enhance conceptual understanding.
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Expert Contributions: Written by internationally recognized authorities in anatomy, embryology, and molecular cell science.
