Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology

2,3004,400

Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology

The book focuses on the role of ubiquitin proteasome system (UPS) in central nervous system. Proteasomes are large multicatalytic proteinase complexes that are found in the cytosol and in the nucleus of eukaryotic cells with a central role in cellular protein turnover. The UPS has a central role in the selective degradation of intracellular proteins. In addition to serving as a means to rapidly eliminate short-lived regulatory proteins involved in cell cycle, cell growth, and differentiation, in periods of stress rapid elimination of denatured, misfolded and damaged proteins by the proteasome becomes a critical determinant of cell fate. These aspects are analysed in central nervous system physiology and pathology.

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Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology

The book focuses on the role of ubiquitin proteasome system (UPS) in central nervous system. Proteasomes are large multicatalytic proteinase complexes that are found in the cytosol and in the nucleus of eukaryotic cells with a central role in cellular protein turnover. The UPS has a central role in the selective degradation of intracellular proteins. In addition to serving as a means to rapidly eliminate short-lived regulatory proteins involved in cell cycle, cell growth, and differentiation, in periods of stress rapid elimination of denatured, misfolded and damaged proteins by the proteasome becomes a critical determinant of cell fate. These aspects are analysed in central nervous system physiology and pathology.

Ubiquitin Proteasome System in the Central Nervous System: From Physiology to Pathology is available at Books Hub Pk for home delivery and Cash on delivery all over Pakistan. All kind of medical books are available.

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Colour Matt Finish, Black & white

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